When treating achilles tendinosis with near infrared laser, the therapeutic interaction takes place in the mitochondria of our cells. Photobiomodulation stimulates the Krebs cycle by dissociating the bond between Cytochrome C oxidase (CcOX) and Nitric Oxide (NO). Krebs cycle stimulation leads to increase ATP production, thus cells will have a store of energy to complete necessary metabolic processes. NO is synthesized in the body and plays an important role in many functions including vasodilation, blood flow, and platelet function.³ Once dissociated from CcOX, NO leads to vasodilation, allowing more blood flow to the affected area. Increased blood flow will allow the migration of tenocytes. Tenocytes are necessary to proliferate and synthesize the extracellular matrix that makes up the tendons in our body, thus repairing microtraumas associated with achilles tendinopathy.