Platelet Rich Plasma Therapy

In this randomized, double-blind study, researchers used the visual analog scale for pain to assess changes in the pain levels of patients with plantar fasciitis.  The patients that received PRP injections showed significantly greater pain reduction than the patients that received placebo saline injections.  The patients that received PRP injections showed similar reductions in pain scores as the patients that received corticosteroid injections at 3 week and 3-month follow ups.

Mahindra P, Yamin M, Selhi HS, Singla S, Soni A. Chronic Plantar Fasciitis: Effect of Platelet-Rich Plasma, Corticosteroid, and Placebo. Orthopedics. 2016;39(2):e285-9. [Pubmed]

This randomized clinical trial divided 160 patients with knee osteoarthritis into 2 groups.  At a 12-month follow up the patients that received PRP injections showed significantly greater reductions in WOMAC pain scores than that patients that received HA injections.

Raeissadat SA, Rayegani SM, Hassanabadi H, et al. Knee Osteoarthritis Injection Choices: Platelet- Rich Plasma (PRP) Versus Hyaluronic Acid (A one-year randomized clinical trial). Clin Med Insights Arthritis Musculoskelet Disord. 2015;8:1-8. [Pubmed]

In this study, 78 patients with bilateral knee OA received either PRP injections or saline injections.  The patients that received PRP injections showed significantly greater reductions in WOMAC pain scores than the patients that received saline injections at 3 week, 3 month, and 6 month follow ups.

Patel S, Dhillon MS, Aggarwal S, Marwaha N, Jain A. Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: a prospective, double-blind, randomized trial. Am J Sports Med. 2013;41(2):356-64. [Pubmed]